Glutathione S-Transferase alpha 3 (GSTA3) (Middle Region) Peptide
GSTA3
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN977726
Aperçu rapide pour Glutathione S-Transferase alpha 3 (GSTA3) (Middle Region) Peptide (ABIN977726)
Antigène
GSTA3
(Glutathione S-Transferase alpha 3 (GSTA3))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- SSLISNFPLL KALKTRISNL PTVKKFLQPG SPRKPPADAK ALEEARKIFR
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-GSTA3 Antibody(ARP48484_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
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Sujet
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Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
Alias Symbols: GSTA3-3, GTA3, MGC22232
Protein Size: 222 -
Poids moléculaire
- 25 kDa
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ID gène
- 2940
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NCBI Accession
- NM_000847, NP_000838
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UniProt
- Q16772
Antigène
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